EARLY OUTCOME OF PATIENT WITH ULCERATIVE COLITIS WHO RECEIVED HIGH DOSE OF STEROID AND UNDERWENT TWO STAGED TOTAL PROCTOCOLECTOMY

Early Outcome of Patient with Ulcerative Colitis who Received High Dose of Steroid and Underwent Two Staged Total Proctocolectomy

Background: Ulcerative colitis (UC) is an idiopathic inflammatory disorder.Currently, the final treatment is colectomy.The aim of this study was to investigate the outcomes of proctocolectomy in patients that used a high dose of prednisolone.Materials and Methods: Seventy-five patients presenting for surgical management of histopathologically prove

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Two years later: journals are not yet enforcing the ARRIVE guidelines on reporting standards for pre-clinical animal studies.

There is growing concern that poor experimental design and lack of transparent reporting contribute to the frequent failure of pre-clinical animal studies to translate into treatments Relations and transformations of extremum energy principles for deformable body/Deformuojamo kūno ekstreminių energinių principų ryšiai ir transformacijos for hu

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Disease-causing Slack potassium channel mutations produce opposite effects on excitability of excitatory and inhibitory neurons

Summary: The KCNT1 gene encodes the sodium-activated potassium channel Slack (KCNT1, KNa1.1), a regulator of neuronal excitability.Gain-of-function mutations in humans cause cortical network hyperexcitability, seizures, and severe intellectual disability.Using a mouse NEUROQUALIMETRY OF INTELLIGENT COMPUTER GAMES model expressing the Slack-R455H mu

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